TMS Therapy involves the use of very short pulses of magnetic energy to stimulate nerve cells in the brain. First used in 1985, TMS Therapy has been used by researchers around the world to help understand the function of different parts of the brain. Neuronetics’ pivotal trial was not the first to investigate the postential antidpressant effects of TMS Therapy, but it was the first one to lead to FDA approval of a TMS device for treatment of outpatients with depression. Results from other trials have encouraged researchers to further investigate TMS Therapy as a treatment for major depression and many studies are still ongoing around the world.
How TMS Therapy Works
The short pulses of magnetic energy produced by NeuroStar TMS Therapy System are aimed by the treating clinician at the structures in the brain thought to control mood. The prefrontal cortex is used to access these structures non-invasively from outside the brain with TMS Therapy. The unique nature of magnetic fields allows them to pass through the skull and into the cortex without being distorted in any way. This facilitates a very focal type of stimulation, minimizing stimulation of brain tissue not involved in mood.
Once inside the brain, the dynamic (rapidly changing) nature of the magnetic pulses induces electrical charges to flow. The amount of electricity created in the brain is very small, and cannot be felt by the patient. When in the correct orientation relative to brain cells (neurons), these very small electric charges can cause the neurons to fire or become active. The objective of TMS Therapy is to stimulate (or activate) brain cells. Patients remain awake and alert during a TMS Therapy procedure.